Dex1: Reeves 1994
12.5% dextrose injection, given extensively under procedural sedation is safe and potentially effective in the treatment of patients with chronic whole body pain that meet the criteria for fibromyalgia. Reeves KD. Treatment of Consecutive Severe Fibromyalgia Patients With Prolotherapy. The Journal of Orthopaedic Medicine 16(3):84-89, 1994.
Our study in Fibromyalgia was published in 1994, based upon the first 2 years of collected data after the primary author learned the technique of reconstructive injection therapy. This was primarily a safety study and the research techniques and measurements were not well developed at that time and this study cannot be used to definitively prove prolotherapy benefit in fibromyalgia. Since then we have learned more effective ways to use prolotherapy in this condition. Combining neurofascial and enthesofascial prolotherapy is more effective. However researching this condition would be very expensive and is not likely to be undertaken for research in a randomized or controlled fashion n the near future. Note also there is much controversy about and yet reason for interest in chronic infectious disorders in this condition, food intolerances, dietary relationships, etc.
The original article was published as: Reeves KD. Treatment of Consecutive Severe Fibromyalgia Patients With Prolotherapy. The Journal of Orthopaedic Medicine 16(3):84-89, 1994.
If you wish to read the original article in full copy, click here. fibromyalgia study.pdf